• Ho Chi Minh City University of Technology, Vietnam (Sep 2011 - Apr 2016)

  • B.Eng. in Mechatronics (Honors)

  • Dissertation: "Remote Human Gaze Estimation with a Single Camera on an Embedded System."

  • Awards and Scholarships:

    • Bronze medal in the National Mechanics Olympics (2014)

    • Second prize in the Machine Design Contest (2014)

    • First prize in the Two-Wheeled Self-Balancing Robot Competition (2015)

    • Scholarships from Kanden System Solution Company and Petro Vietnam Exploration Production Corporation (2015)

    • Annual Scholarships from Ho Chi Minh City University of Technology (2011-2016)

    • Special Award in "The International Capstone Design Contest on Renewable Energy Technology" (2016)

• Nanyang Technological University, Singapore (Jul 2016 - Feb 2021)

  • Ph.D. in Mechanical Engineering

  • Dissertation: "Multidimensional Patterning and Manipulation of Microparticles and Cells using Surface Acoustic Waves."

  • Awards and Scholarships:

    • NTU Research Scholarship (Jul 2016 - Jul 2020)

    • Silver medal in the MAE NTU Football Competition (2016)

    • Certificate of University Teaching for Teaching Assistants (2017)

    • "Best Student Paper Award" in Electrophoresis journal (2021)

AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (A*STAR) – Singapore                        

Scientist

• Led a team in developing a scalable transduction system aimed at enhancing viral transduction efficiency in T-cell therapy manufacturing.

• Designed and implemented a next-gen continuous in-line system for low-pH viral inactivation during monoclonal antibodies (mAbs) production, ensuring optimal product quality and safety.

• Awarded the Early Career Researchers (ERCs) Grant from A*STAR Research Office as the Principal Investigator to develop a novel and high-throughput microfluidic transduction device.

• Review Editor of Journal Frontiers in Acoustics.

SINGAPORE-MIT ALLIANCE FOR RESEARCH AND TECHNOLOGY (SMART) – Singapore

Postdoctoral Associate  

• Developed a platform technology that utilizes Raman spectroscopy to quantify the critical quality attributes (CQAs) of neural stem cells and their progenitors/differentiated cell products, enabling the detection of undifferentiated cells.

• Developed microfluidic cell sorting technologies designed to eliminate undifferentiated cells in a label-free, high-throughput manner, thereby enhancing the quality of cell therapy manufacturing for neural stem/progenitor cells.

• Recipient of the "Best Poster Presentation Award" at the Tissue Engineering and Regenerative Medicine International Society Asia-Pacific Chapter Conference (10/2022).

NANYANG TECHNOLOGICAL UNIVERSITY (NTU) – Singapore

PhD Candidate 

• Studied multidimensional patterning and manipulating of microparticles and cells using surface acoustic waves (PhD project).

• Developed a reusable microfluidic device capable of precisely manipulating cells to form intricate three-dimensional patterns within scaffold-based hydrogels, advancing the field of bio-structure building and tissue engineering.

• Developed a highly efficient microfluidic device for controlling the three-dimensional positioning of individual cells in fluid, enabling the development of automated cell analysis systems and integration into lab-on-chip and organ-on-chip devices.

• Conceived and executed an experimental investigation proposal to secure academic research funding (funded).

SHISEIDO VIETNAM INC – Vietnam

Engineering Intern                                                                                   

• Enhanced production line efficiency by implementing process improvements and optimizing workflow.

• Designed and developed a highly efficient bottle air jet cleaning machine, reducing cleaning time and ensuring product quality.

• Conducted comprehensive analysis of air flow patterns inside bottles, identifying areas for improvement and implementing corrective measures to enhance bottle cleaning efficiency.

HO CHI MINH CITY UNIVERSITY OF TECHNOLOGY – Vietnam

Robotics Club Member

• Led the design and development of an autonomous robot for the team's participation in the ABU Robocon 2013 Contest (Spring 2013).

• Designed, manufactured, and operated a highly efficient line-following robot during the summer of 2013, demonstrating expertise in robotics engineering and precision control systems.

Undergraduate Research Assistant to Dr. Doan The Thao

• Contributed to the design and fabrication of a cutting-edge coconut paring machine.

• Led the design, manufacturing, and operation of a two-wheel self-balance robot.

• Implemented computer vision techniques to develop a defect detection system for fabrics, improving quality control processes.

• Designed, fabricated, and operated an embedded system with a single camera for accurate eye-gaze estimation for human-computer interaction research.

• Teaching assistant, Behavior of Composite Beam, Nanyang Technological University (Spring, 2018).

• Teaching assistant, Dynamic Vibration Absorber, Nanyang Technological University (Spring and Fall, 2019).

• Teaching assistant, Introduction to Engineering Mechanics, Nanyang Technological University (Spring, 2020).

• Mentored a total of 8 undergraduate students and 2 master's students on their research projects, Nanyang Technological University (2016-2020). 

Technical Skills:

• Software: MS Office, programming languages (C/C++/C#, Python, Visual Studio, MATLAB), mechanical design (AutoCAD, Autodesk Inventor, Fusion), electronic circuit design (Altium Designer, OrCAD, Proteus), and image processing (MATLAB, OpenCV, ImageJ, Fiji).

• MEMS/Microfluidic fabrication processes, modeling and simulation using Autodesk Inventor, COMSOL, and ANSYS.

• Machining and electronic skills, cell culture/handling, and machine learning.

General Skills:

• Problem-solving, presentation skills, logical, independent and self-motivated researcher, effective teamwork, curious and open-minded thinking, and passion for technological innovation.

• Member of Robotics Club in Ho Chi Minh University of Technology, Vietnam (2012-2014).

• Member of Robotic team participated the Asia-pacific robot contest (ABU ROBOCON) (2013).

• Mathematics tutor for 3 years (2012-2014).

• Internship at SHISEIDO VIETNAM INC (Summer 2015).

• President of Dong-Hanh Singapore Association, host of a fund-raising event from Vietnamese community in Singapore to help brilliant and underprivileged students in Vietnam to pursuit their future career and dream (donghanh.net) (2016-2019).

• Member of the International Society for Cell & Gene Therapy (ISCT).

Selected Publications:

• Tan Dai Nguyen, Van Thai Tran, YongQing Fu, Hejun Du (2018). "Patterning and manipulating microparticles into a three-dimensional matrix using standing surface acoustic waves." Applied Physics Letters, 112(21), 213507. ISSN 0003-6951(link).

• Xiang Tao, Tan Dai Nguyen, Hao Jin, Ran Tao, Jingting Luo, Xin Yang, Hamdi Torun, Jian Zhou, Shuyi Huang, Lin Shi, Des Gibson, Michael Cooke, Hejun Du, Shurong Dong, Jikui Luo, YongQing Fu (2019). "3D patterning/manipulating microparticles and yeast cells using ZnO/Si thin film surface acoustic waves." Sensors and Actuators B: Chemical, Volume 299, 126991. ISSN 0925-4005 (link).

• Tan Dai Nguyen, Yong Qing Fu, Archana Gautam, Sanam Pudasaini, Van Thai Tran, Hejun Du (2020). "Acoustofluidic closed-loop control of microparticles and cells using standing surface acoustic waves." Sensors and Actuators B: Chemical, 128143 (link).

• Tan Dai Nguyen, Yong Qing Fu, Jia Min Lee, Van Thai Tran, Sanam Pudasaini, Archana Gautam, Hejun Du. "Large-scale fabrication of three-dimensional scaffold-based patterns of microparticles and breast cancer cells using reusable acoustofluidic device." Advanced Engineering Materials, 23, 2001377 (link).

• Tan Dai Nguyen, Yong Qing Fu, Van Thai Tran, Hejun Du. "Manipulation of self-assembled three-dimensional architecture in reusable acoustofluidic device." ELECTROPHORESIS, 42, 2375-2382 (link).

• Tan Dai Nguyen, Wai Hon Chooi, Hyungkook Jeon, Jiahui Chen, Daniel Ninio Roxby, Jerome Tan, Zu Yao, Shi Yan Ng, Sing Yian Chew, Jongyoon Han. "Label-Free and High-Throughput Removal of Residual Undifferentiated Cells From iPSC-Derived Spinal Cord Progenitor Cells." Stem Cells Translational Medicine 2024 (link), featured on MIT News).

• Sixun Chen*, Tan Dai Nguyen*, Kang-Zheng Lee, Dan Liu. "T cell differentiation in adoptive immunotherapy manufacturing: process control strategies and analytical technologies." Biotechnology Advances (in revision, *co-first author).

Patents:

• WO 2024076302A1: Method for Removing Undifferentiated Cells (link).

• WO2024076963A1: Micro Magnetic Resonance Relaxometry (MRR) for Rapid and Non-Invasive Detection of iPSC Quality and Differentiation (link).

• Dinh Quang Tri, Tan Dai Nguyen, Doan The Thao. 3D eye gaze estimation with a single camera on arm board embedded Linux platform.  National Conference on Machines and Mechanisms, 2015, Vietnam.

• Tan Dai Nguyen, Huu Duoc Nguyen, Doan The Thao. Remote gaze estimation based on face and iris detection under IR light. Vietnam Conference on Mechatronics - VCM 2016, Vietnam.

• Tan Dai Nguyen, Van Thai Tran, Yong Qing Fu, Hejun Du. The 3D patterning of microparticles inside millimeter height of chamber using standing surface acoustic wave. Acousticfluidics 2018, Lille, France.

• Tan Dai Nguyen, Van Thai Tran, Yong Qing Fu, Hejun Du. Patterning and manipulating microparticles into a three-dimensional matrix using standing surface acoustic waves for biomedical engineering applications. International Conference on Materials for Advanced Technologies 2019, Singapore.

• Tan Dai Nguyen, Wai Hon Chooi, Jiahui Chen, Daniel Ninio Roxby, Jerome Tan Zu Yao, Hyungkook Jeon, Shi Yan Ng, Sing Yian Chew, Jongyoon Han. Label‐free and high‐throughput removal of residual undifferentiated iPSCs from their differentiated progenitor cells by inertial microfluidic cell sorter. Tissue Engineering and Regenerative Medicine International Society Asia‐Pacific Chapter Conference 2022.

• Tan Dai Nguyen, Jiahui Chen, Quan Liu, Sing Yian Chew, Jongyoon Han. Label‐free detection of residual undifferentiated iPSCs from their differentiated progenitor cells by microfluidic Raman spectroscopy. Tissue Engineering and Regenerative Medicine International Society Asia‐Pacific Chapter Conference 2022. 

Email: tandai@outlook.sg

LinkedIn: Tan Dai Nguyen